Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18657166 | 0.75 | GFER (0.54) | GFERMAOBMAOAALDH1A1CYP19A1 | |
| SCHEMBL5962 | 0.71 | GFER (0.68) | GFERMAOBMAOAALDH1A1CYP19A1 | |
| SCHEMBL20712855 | 0.70 | GFER (0.48) | GFERMAOBMAOAALDH1A1CYP19A1 | |
| SCHEMBL19088829 | 0.70 | ESRRG (0.50) | GFERMAOBMAOAESRRGALDH1A1 | |
| SCHEMBL160035 | 0.70 | ESRRG (0.54) | GFERESRRGALDH1A1TSHRPPIB | |
| SCHEMBL160330 | 0.70 | RAB9A (0.55) | ESRRGALDH1A1LMNACYP3A4TDP1 | |
| SCHEMBL27576975 | 0.70 | GFER (0.59) | GFERMAOBMAOAESRRGALDH1A1 | |
| SCHEMBL29155827 | 0.69 | GFER (0.65) | GFERMAOBMAOAALDH1A1CYP19A1 | |
| SCHEMBL17751262 | 0.69 | GFER (0.46) | GFERPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL15109535 | 0.69 | HPGD (0.49) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262789-A1 | ANTITUMOR COMPOUND AND USE THEREOF | 明慧医药（杭州）有限公司 | 2022-12-22 | — | — | WO | disclosed |