Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.37 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 8/20 | 0.35 |
| ▸ | OAT | P04181 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153255 | 0.76 | — | — | |
| Glycine SCHEMBL25242169 | 0.73 | GLRA1 (0.40) | GLRA1SLC6A9OR51E2ITGB3ITGB2 | |
| Glycine SCHEMBL2116443 | 0.72 | — | — | |
| Glycine SCHEMBL93765 | 0.72 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2SLC6A12SLC6A11 | |
| Glycine SCHEMBL30179260 | 0.72 | — | — | |
| Glycine SCHEMBL391027 | 0.72 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2SLC6A12SLC6A11 | |
| Glycine SCHEMBL6675874 | 0.72 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2SLC6A12SLC6A11 | |
| Glycine SCHEMBL3640989 | 0.72 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2SLC6A12SLC6A11 | |
| Glycine SCHEMBL391786 | 0.72 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2SLC6A12SLC6A11 | |
| Glycine SCHEMBL6163 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107404921-B | Sugar-dipeptide conjugates | 雀巢产品有限公司 | 2020-12-25 | — | — | CN | claimed |
| WO-2020241565-A1 | COMPOSITION, GAS SEPARATION MEMBRANE AND METHOD FOR PRODUCING SAME, AND GAS SEPARATION DEVICE | 住友化学株式会社 | 2020-12-03 | — | — | WO | claimed |
| WO-2020241563-A1 | COMPOSITION, GAS SEPARATION FILM AND PRODUCTION METHOD THEREFOR, AND GAS SEPARATION DEVICE | 住友化学株式会社 | 2020-12-03 | — | — | WO | claimed |
| US-10258071-B2 | Sugar-dipeptide conjugates | NESTEC S.A. (CH) | 2019-04-16 | — | — | US | claimed |
| EP-3270711-B1 | SUGAR-DIPEPTIDE CONJUGATES | NESTEC SA (CH) | 2018-12-05 | — | — | EP | claimed |
| US-20180055078-A1 | SUGAR-DIPEPTIDE CONJUGATES | Société des Produits Nestlé S.A. (CH) | 2018-03-01 | — | — | US | claimed |
| EP-3270711-A1 | SUGAR-DIPEPTIDE CONJUGATES | Nestec S.A. (CH) | 2018-01-24 | — | — | EP | claimed |
| WO-2016146432-A1 | SUGAR-DIPEPTIDE CONJUGATES | NESTEC S.A. (CH) | 2016-09-22 | — | — | WO | claimed |
| US-20230390711-A1 | RESIN COMPOSITION FOR GAS SEPARATION MEMBRANE AND GAS SEPARATION MEMBRANE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-12-07 | — | — | US | disclosed |
| US-20230285906-A1 | GAS SEPARATION MEMBRANE AND METHOD FOR MANUFACTURING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-09-14 | — | — | US | disclosed |
| CN-116194197-A | Resin composition for gas separation membrane and gas separation membrane | 住友化学株式会社 | 2023-05-30 | — | — | CN | disclosed |
| EP-4183476-A1 | RESIN COMPOSITION FOR GAS SEPARATION MEMBRANE AND GAS SEPARATION MEMBRANE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-24 | — | — | EP | disclosed |
| EP-4183477-A1 | GAS SEPARATION MEMBRANE AND METHOD FOR PRODUCING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-24 | — | — | EP | disclosed |
| CN-116133740-A | Gas separation membrane and method for producing same | 住友化学株式会社 | 2023-05-16 | — | — | CN | disclosed |
| US-5585396-A | SIDE EFFECT REDUCTION | WAKE FOREST UNIVERSITY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5561110-A | ADMINISTERING OLIGOPEPTIDE | PEPTIDE TECHNOLOGY LIMITED (AU) | 1996-10-01 | — | — | US | disclosed |
| US-5512592-A | Method of producing cardiotonic effect and improving cardiac contractile function by administration of carnosine | WAKE FOREST UNIVERSITY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0666753-A1 | METHOD FOR THE TREATMENT OF THE COMPLICATIONS AND PATHOLOGY OF DIABETES | PEPTIDE TECHNOLOGY LTD (AU) | 1995-08-16 | — | — | EP | disclosed |
| EP-0666753-A4 | METHOD FOR THE TREATMENT OF THE COMPLICATIONS AND PATHOLOGY OF DIABETES. | PEPTIDE TECHNOLOGY LTD (AU) | 1995-01-26 | — | — | EP | disclosed |
| WO-1993004690-A1 | METHOD FOR THE TREATMENT OF THE COMPLICATIONS AND PATHOLOGY OF DIABETES | PEPTIDE TECHNOLOGY LIMITED (AU) | 1993-03-18 | — | — | WO | disclosed |