Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23683108 | 1.00 | GAA (0.57) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL2011681 | 0.94 | MMP1 (0.55) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL15145874 | 0.93 | GAA (0.60) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL9780583 | 0.91 | ALDH1A1 (0.67) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL15145875 | 0.86 | CYP3A4 (0.70) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL12849347 | 0.83 | ALDH1A1 (0.66) | ALDH1A1PKMKMT2AMEN1KDM4E | |
| SCHEMBL11629929 | 0.83 | ALDH1A1 (0.59) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL23683085 | 0.83 | GAA (0.61) | GAAALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL17599857 | 0.83 | ALDH1A1 (0.66) | ALDH1A1PKMKMT2AMEN1KDM4E | |
| SCHEMBL10078758 | 0.83 | ALDH1A1 (0.75) | GAAALDH1A1PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |