Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24762713 | 0.89 | CNR2 (0.37) | EPHX2CNR2EPHX1DPP4DPP7 | |
| SCHEMBL27238488 | 0.85 | KDM1A (0.40) | EPHX2EPHX1KDM1A | |
| SCHEMBL24762211 | 0.82 | GPR119 (0.47) | RORC | |
| SCHEMBL24762715 | 0.81 | CA12 (0.37) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL24762643 | 0.80 | CA12 (0.40) | ALKEPHX2EPHX1LMNADPP4 | |
| SCHEMBL27238558 | 0.79 | GPR183 (0.39) | LMNACA12CA1CA2CA7 | |
| SCHEMBL29764498 | 0.78 | CHRM2 (0.44) | LMNAPOLBALDH1A1 | |
| SCHEMBL24762729 | 0.74 | PLCG1 (0.35) | LMNAHTTPOLBCA2ALDH1A1 | |
| SCHEMBL24762622 | 0.73 | RORC (0.38) | ALKEPHX2CNR2LMNADPP4 | |
| SCHEMBL24761962 | 0.73 | CACNA1B (0.43) | LMNAALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |