Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24762619 | 0.85 | HTR2A (0.45) | CA12CA1CA2CA4CA5A | |
| SCHEMBL27238488 | 0.84 | KDM1A (0.40) | KDM1AMEN1KMT2ARIPK1 | |
| SCHEMBL27238539 | 0.83 | PKM (0.40) | ALDH1A1LMNASMN1; SMN2HPGDFKBP1A | |
| SCHEMBL24762728 | 0.81 | ALK (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24762713 | 0.81 | CNR2 (0.37) | ALDH1A1KDM1AKMT2ARIPK1 | |
| SCHEMBL27238543 | 0.79 | HTT (0.47) | MCL1BCL2A1KDM1ATHRB | |
| SCHEMBL27238545 | 0.78 | CA12 (0.41) | CA12CA1CA2CA4CA5A | |
| SCHEMBL27238639 | 0.78 | ALDH1A1 (0.36) | CA12CA1CA2CA4CA5A | |
| SCHEMBL24762182 | 0.77 | PKM (0.55) | ALDH1A1LMNANPC1KMT2AGAA | |
| SCHEMBL24763408 | 0.76 | KDM1A (0.47) | ALDH1A1LMNASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |