Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472773 | 0.94 | CA2 (0.52) | CA2CA1CA9CA7CA12 | |
| SCHEMBL675017 | 0.88 | MMP9 (0.56) | CA2CA1MMP9MMP8MMP13 | |
| SCHEMBL9395046 | 0.88 | MMP9 (0.56) | CA2CA1MMP9MMP8MMP13 | |
| SCHEMBL10947029 | 0.82 | MMP9 (0.51) | MMP9MMP8MMP13LMNA | |
| SCHEMBL10942632 | 0.82 | MMP9 (0.51) | MMP9MMP8MMP13LMNA | |
| SCHEMBL10950538 | 0.82 | MMP9 (0.51) | MMP9MMP8MMP13LMNA | |
| SCHEMBL812903 | 0.82 | LMNA (0.55) | MMP9MMP8MMP13GAALMNA | |
| SCHEMBL27466843 | 0.82 | CA2 (0.50) | CA2CA1CA9CA7CA12 | |
| SCHEMBL1404164 | 0.80 | EPHX1 (0.53) | MMP9MMP8MMP13SMN1; SMN2LMNA | |
| SCHEMBL21359023 | 0.80 | EPHX1 (0.53) | MMP9MMP8MMP13SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373622-A2 | CA-IX SPECIFIC RADIOPHARMACEUTICALS FOR THE TREATMENT AND IMAGING OF CANCER | Molecular Insight Pharmaceuticals, Inc. (US) | 2011-10-12 | — | — | EP | disclosed |