Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170030 | 0.84 | ROCK2 (0.33) | ROCK2ROCK1 | |
| SCHEMBL680295 | 0.83 | L3MBTL3 (0.38) | — | |
| SCHEMBL13791631 | 0.81 | — | — | |
| SCHEMBL17404851 | 0.79 | — | — | |
| SCHEMBL19960784 | 0.76 | L3MBTL3 (0.34) | — | |
| SCHEMBL16904633 | 0.76 | MCHR1 (0.33) | — | |
| SCHEMBL20047656 | 0.76 | — | — | |
| SCHEMBL16904640 | 0.76 | ATM (0.31) | — | |
| SCHEMBL16904637 | 0.76 | ATM (0.31) | — | |
| SCHEMBL28172494 | 0.76 | ATM (0.34) | GRIN2DGRIN3BCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262784-A1 | IDH MUTANT INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2022-12-22 | — | — | WO | disclosed |