SCHEMBL19960784

SCHEMBL19960784

CN(C)C1CCCN(C(C)(C)C)CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 2/20 0.34
PIM1 P11309 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680295 0.91 L3MBTL3 (0.38) L3MBTL3L3MBTL1
SCHEMBL23761690 0.83 PIM1 (0.34) PIM1
SCHEMBL9883843 0.83 PIM1 (0.34) PIM1
SCHEMBL15882974 0.83 PIM1 (0.34) PIM1
SCHEMBL22166558 0.80 L3MBTL3 (0.42) L3MBTL3L3MBTL1
SCHEMBL8260570 0.78 HRH4 (0.33) L3MBTL3
SCHEMBL679560 0.78 HRH4 (0.33) L3MBTL3
SCHEMBL731310 0.78 HRH4 (0.33) L3MBTL3
SCHEMBL13791631 0.76
SCHEMBL24764256 0.76 ROCK2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159491-A1 Antimicrobial Compounds and Methods NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-05-25 US disclosed
US-9969719-B2 Substituted 2-hydrogen-pyrazole derivative serving as anticancer drug CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2018-05-15 US disclosed
US-9969719-B2 Substituted 2-hydrogen-pyrazole derivative serving as anticancer drug CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2018-05-15 US disclosed
US-20180072707-A1 SUBSTITUTED 2-HYDROGEN-PYRAZOLE DERIVATIVE SERVING AS ANTICANCER DRUG CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2018-03-15 US disclosed
US-20180072707-A1 SUBSTITUTED 2-HYDROGEN-PYRAZOLE DERIVATIVE SERVING AS ANTICANCER DRUG CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072707-A1 SUBSTITUTED 2-HYDROGEN-PYRAZOLE DERIVATIVE SERVING AS ANTICANCER DRUG CDK4, CDK6, CDK3 L3MBTL3 3022/4885PIM1 158/4885L3MBTL1 3069/4885
US-20230159491-A1 Antimicrobial Compounds and Methods MPO, NISCH, RPN2 L3MBTL3 1338/4885PIM1 505/4885L3MBTL1 1507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.