Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263454 | 0.90 | KDM4E (0.32) | — | |
| SCHEMBL514781 | 0.88 | KDM4E (0.31) | — | |
| SCHEMBL10751335 | 0.85 | KDM4E (0.35) | — | |
| SCHEMBL515437 | 0.84 | KDM4E (0.34) | — | |
| SCHEMBL9396652 | 0.83 | — | — | |
| SCHEMBL9396230 | 0.83 | — | — | |
| SCHEMBL10748964 | 0.81 | ACHE (0.32) | — | |
| SCHEMBL10751317 | 0.81 | ACHE (0.32) | — | |
| SCHEMBL9396624 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL27994197 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374031-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010071691-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2010-06-24 | — | — | WO | disclosed |