SCHEMBL263454

SCHEMBL263454

C=C(C)C(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514781 0.98 KDM4E (0.31) KDM4EMAPK1HIF1AACHE
SCHEMBL10751335 0.95 KDM4E (0.35) KDM4EMAPK1HIF1AACHE
SCHEMBL515437 0.93 KDM4E (0.34) KDM4EMAPK1HIF1A
SCHEMBL9396230 0.92
SCHEMBL9396652 0.92
SCHEMBL10748964 0.90 ACHE (0.32) ACHE
SCHEMBL10751317 0.90 ACHE (0.32) ACHE
Acrylamide SCHEMBL2476543 0.90 ALDH1A1 (0.31)
SCHEMBL9396624 0.87 KDM4E (0.31) KDM4EMAPK1HIF1A
SCHEMBL27994197 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 984 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2187243-B2 Colored ink for pad transfer printing of silicone hydrogel lenses ALCON INC (CH) 2025-07-09 EP claimed
WO-2025082614-A1 COLLOIDAL ION-CAPPED PB CHALCOGENIDE NANOCRYSTALS FOR SWIR APPLICATIONS QDI SYSTEMS B.V (NL) 2025-04-24 WO claimed
WO-2025082611-A1 COLLOIDAL ION-CAPPED PB CHALCOGENIDE NANOCRYSTALS FOR X-RAY APPLICATIONS QDI SYSTEMS B.V (NL) 2025-04-24 WO claimed
CN-119638918-A Colored silicon polymer material and preparation method thereof 江苏天眼医药科技股份有限公司 2025-03-18 CN claimed
CN-119569962-A Silicon polymer material and preparation method thereof 烟台爱博诺德医用材料有限公司 2025-03-07 CN claimed
EP-3635450-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-05-08 EP claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
US-20230364832-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2023-11-16 US claimed
WO-2005098478-A1 COLORED INK FOR PAD TRANSFER PRINTING OF SILICONE HYDROGEL LENSES NOVARTIS AG (CH) 2005-10-20 WO claimed
US-20050218536-A1 Colored ink for pad transfer printing of silicone hydrogel lenses ALCON INC. (CH) 2005-10-06 US claimed
EP-0675910-B1 NOVEL MACROMONOMERS BAUSCH & LOMB (US) 1997-09-17 EP claimed
EP-0675910-A1 NOVEL MACROMONOMERS. BAUSCH & LOMB (US) 1995-10-11 EP claimed
EP-0387706-B1 Oxygen permeable hard contact lens KURARAY CO (JP) 1994-10-26 EP claimed
US-5336797-A Polymerizable with acrylic monomers and acrylated polyethers; contact lenses BAUSCH & LOMB INCORPORATED (US) 1994-08-09 US claimed
WO-1994015980-A1 NOVEL MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1994-07-21 WO claimed
US-5162391-A Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer KURARAY CO., LTD. (JP) 1992-11-10 US claimed
EP-0387706-A2 Oxygen permeable hard contact lens KURARAY CO., LTD. (JP) 1990-09-19 EP claimed
US-4711943-A IMPROVED OXYGEN PERMEABILITY AND STABILITY SOLA U.S.A. INC. (US) 1987-12-08 US claimed