SCHEMBL515437

SCHEMBL515437

C=C(C)C(=O)NCCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](CCCCNC(=O)C(=C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
PAOX Q6QHF9 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10751335 0.98 KDM4E (0.35) KDM4EMAPK1HIF1APAOX
SCHEMBL514781 0.95 KDM4E (0.31) KDM4EMAPK1HIF1A
SCHEMBL263454 0.93 KDM4E (0.32) KDM4EMAPK1HIF1A
SCHEMBL9396652 0.86
SCHEMBL9396230 0.86
SCHEMBL27994558 0.86
SCHEMBL10754926 0.85 KDM4E (0.35) KDM4EMAPK1HIF1APAOX
SCHEMBL10751317 0.84 ACHE (0.32)
SCHEMBL10748964 0.84 ACHE (0.32)
Acrylamide SCHEMBL2476543 0.84 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20250387989-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2025-12-25 US claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-12420501-B2 Silicone hydrogel lenses with water-rich surfaces ALCON INC. (CH) 2025-09-23 US claimed
US-20220281190-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2022-09-08 US claimed
US-11364695-B2 Silicone hydrogel lenses with water-rich surfaces ALCON INC. (CH) 2022-06-21 US claimed
US-20200339836-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2020-10-29 US claimed
US-10781340-B2 Silicone hydrogel lenses with water-rich surfaces ALCON INC. (CH) 2020-09-22 US claimed
US-10513628-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2019-12-24 US claimed
US-20190055427-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2019-02-21 US claimed
US-10131815-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2018-11-20 US claimed
US-20180044549-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2018-02-15 US claimed
EP-2513711-B1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS NOVARTIS AG (CH) 2017-07-12 EP claimed
US-9005492-B2 Methods for making silicone hydrogel lenses from water-based lens formulations NOVARTIS AG (CH) 2015-04-14 US claimed
US-8883051-B2 Methods for increasing the ion permeability of contact lenses NOVARTIS AG (CH) 2014-11-11 US claimed
US-20110140292-A1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS ALCON INC. (CH) 2011-06-16 US claimed
US-20110133350-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES ALCON INC. (CH) 2011-06-09 US claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US disclosed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US disclosed
US-20250387989-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2025-12-25 US disclosed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP disclosed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP disclosed
US-12420501-B2 Silicone hydrogel lenses with water-rich surfaces ALCON INC. (CH) 2025-09-23 US disclosed
EP-2705808-B1 Silicone hydrogel lenses with water-rich surfaces ALCON INC (CH) 2024-05-01 EP disclosed
US-11828915-B2 Methods and compositions for improved comfort contact lens UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-28 US disclosed
EP-3197940-B1 POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS ALCON INC (CH) 2023-02-15 EP disclosed
US-20220413189-A1 METHODS AND COMPOSITIONS FOR IMPROVED COMFORT CONTACT LENS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-12-29 US disclosed
US-11480714-B2 Methods and compositions for improved comfort contact lens UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2022-10-25 US disclosed
US-20220281190-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2022-09-08 US disclosed
US-11364695-B2 Silicone hydrogel lenses with water-rich surfaces ALCON INC. (CH) 2022-06-21 US disclosed
EP-3344302-B1 SOFT SILICONE MEDICAL DEVICES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC (CH) 2022-04-13 EP disclosed
US-11002884-B2 Method for applying stable coating on silicone hydrogel contact lenses ALCON INC. (CH) 2021-05-11 US disclosed
US-11001647-B2 Soft silicone medical devices ALCON INC. (CH) 2021-05-11 US disclosed
EP-3268804-B1 MESH SIZE CONTROL OF LUBRICATION IN GEMINI HYDROGELS UNIV FLORIDA (US) 2020-11-04 EP disclosed
US-10823983-B2 UV-absorbing vinylic monomers and uses thereof ALCON INC. (CH) 2020-11-03 US disclosed
US-20200339836-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2020-10-29 US disclosed
US-10781340-B2 Silicone hydrogel lenses with water-rich surfaces ALCON INC. (CH) 2020-09-22 US disclosed
US-20200284951-A1 METHODS AND COMPOSITIONS FOR IMPROVED COMFORT CONTACT LENS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2020-09-10 US disclosed
EP-3419961-B1 UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC (CH) 2020-09-02 EP disclosed
US-10723842-B2 Mesh size control of lubrication in gemini hydrogels UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2020-07-28 US disclosed
EP-3391101-B1 METHOD FOR APPLYING STABLE COATING ON SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2020-07-08 EP disclosed
EP-3419966-B1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC (CH) 2020-03-25 EP disclosed
US-10598825-B2 Soft silicone medical devices with durable lubricious coatings thereon ALCON INC. (CH) 2020-03-24 US disclosed
US-10513628-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2019-12-24 US disclosed
EP-2638878-B1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES NOVARTIS AG (CH) 2019-10-23 EP disclosed
US-10449740-B2 Method for applying stable coating on silicone hydrogel contact lenses NOVARTIS AG (CH) 2019-10-22 US disclosed
EP-3186070-B1 METHOD FOR APPLYING STABLE COATING ON SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2019-09-25 EP disclosed
US-20190257980-A1 SOFT SILICONE MEDICAL DEVICES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC. (CH) 2019-08-22 US disclosed
US-10338408-B2 Method for making improved UV-absorbing ophthalmic lenses NOVARTIS AG (CH) 2019-07-02 US disclosed
US-10324233-B2 Soft silicone medical devices with durable lubricious coatings thereon NOVARTIS AG (CH) 2019-06-18 US disclosed
US-20190179170-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC. (CH) 2019-06-13 US disclosed
US-20190177444-A1 SOFT SILICONE MEDICAL DEVICES ALCON INC. (CH) 2019-06-13 US disclosed
EP-2625216-B1 POLYMERISABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS NOVARTIS AG (CH) 2019-06-05 EP disclosed
EP-3486711-A1 LENS-FORMING MATERIALS COMPRISING PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES Novartis AG (CH) 2019-05-22 EP disclosed
US-10268053-B2 UV/visible-absorbing vinylic monomers and uses thereof NOVARTIS AG (CH) 2019-04-23 US disclosed
US-10266445-B2 Method for producing contact lenses with durable lubricious coatings thereon NOVARTIS AG (CH) 2019-04-23 US disclosed
US-10253112-B2 Soft silicone medical devices NOVARTIS AG (CH) 2019-04-09 US disclosed
US-10254567-B2 UV-absorbing vinylic monomers and uses thereof NOVARTIS AG (CH) 2019-04-09 US disclosed
US-20190055427-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2019-02-21 US disclosed
US-10131815-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2018-11-20 US disclosed
US-10081142-B2 Method for producing contact lenses with a lubricious surface NOVARTIS AG (CH) 2018-09-25 US disclosed
EP-3062979-B1 METHOD FOR PRODUCING OPHTHALMIC LENSES NOVARTIS AG (CH) 2018-08-29 EP disclosed
EP-2625217-B1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS NOVARTIS AG (CH) 2018-07-04 EP disclosed
US-20180141293-A1 METHOD FOR MAKING OPHTHALMIC LENSES ALCON INC. (CH) 2018-05-24 US disclosed
EP-2625218-B1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2018-04-25 EP disclosed
US-9921340-B2 Water-processable silicone-containing prepolymers and uses thereof NOVARTIS AG (CH) 2018-03-20 US disclosed
US-9919456-B2 Method for producing ophthalmic lenses NOVARTIS AG (CH) 2018-03-20 US disclosed
US-20180044549-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2018-02-15 US disclosed
US-20180030209-A1 Mesh Size Control of Lubrication in Gemini Hydrogels UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2018-02-01 US disclosed
US-9816009-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2017-11-14 US disclosed
EP-2432821-B1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2017-08-30 EP disclosed
US-20170242274-A1 UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC. (CH) 2017-08-24 US disclosed
US-20170240658-A1 SOFT SILICONE MEDICAL DEVICES ALCON INC. (CH) 2017-08-24 US disclosed
US-20170242275-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC. (CH) 2017-08-24 US disclosed
US-9720139-B2 Polymerizable polysiloxanes with hydrophilic substituents NOVARTIS AG (CH) 2017-08-01 US disclosed
US-20170176643-A1 POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS ALCON INC. (CH) 2017-06-22 US disclosed
US-20170165932-A1 METHOD FOR APPLYING STABLE COATING ON SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2017-06-15 US disclosed
US-20170165930-A1 METHOD FOR PRODUCING CONTACT LENSES WITH A LUBRICIOUS SURFACE ALCON INC. (CH) 2017-06-15 US disclosed
US-9637582-B2 Polymerizable polysiloxanes with hydrophilic substituents NOVARTIS AG (CH) 2017-05-02 US disclosed
US-20170068018-A1 SOFT SILICONE MEDICAL DEVICES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC. (CH) 2017-03-09 US disclosed
EP-2510052-B1 A SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING NOVARTIS AG (CH) 2017-02-08 EP disclosed
EP-2932314-B1 METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2017-02-01 EP disclosed
US-20160377885-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2016-12-29 US disclosed
US-20160326046-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC. (CH) 2016-11-10 US disclosed
US-9411171-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2016-08-09 US disclosed
EP-2598937-B1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2016-06-29 EP disclosed
US-9341744-B2 Amphiphilic polysiloxane prepolymers and uses thereof NOVARTIS AG (CH) 2016-05-17 US disclosed
US-20160097938-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2016-04-07 US disclosed
US-20160097939-A1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES ALCON INC. (CH) 2016-04-07 US disclosed
US-20160090432-A1 POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS ALCON INC. (CH) 2016-03-31 US disclosed
US-20160062142-A1 METHOD FOR APPLYING STABLE COATING ON SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2016-03-03 US disclosed
US-20160033683-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2016-02-04 US disclosed
US-9244195-B2 Silicone hydrogel lenses with nano-textured surfaces NOVARTIS AG (CH) 2016-01-26 US disclosed
US-9244200-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2016-01-26 US disclosed
US-9187601-B2 Water-processable silicone-containing prepolymers and uses thereof NOVARTIS AG (CH) 2015-11-17 US disclosed
EP-2432808-B1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2015-10-21 EP disclosed
US-9109091-B2 Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups NOVARTIS AG (CH) 2015-08-18 US disclosed
EP-2718751-B1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES NOVARTIS AG (CH) 2015-07-22 EP disclosed
US-9066981-B2 Actinically-crosslinkable siloxane-containing copolymers NOVARTIS AG (CH) 2015-06-30 US disclosed
US-9052440-B2 Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains NOVARTIS AG (CH) 2015-06-09 US disclosed
US-20150152228-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS ALCON INC. (CH) 2015-06-04 US disclosed
US-20150153482-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2015-06-04 US disclosed
US-20150115485-A1 METHOD FOR PRODUCING OPHTHALMIC LENSES ALCON INC. (CH) 2015-04-30 US disclosed
US-20150092156-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2015-04-02 US disclosed
US-8993651-B2 Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups NOVARTIS AG (CH) 2015-03-31 US disclosed
US-8987403-B2 Amphiphilic polysiloxane prepolymers and uses thereof NOVARTIS AG (CH) 2015-03-24 US disclosed
US-8939577-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2015-01-27 US disclosed
US-20140350124-A1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS ALCON INC. (CH) 2014-11-27 US disclosed
US-8883051-B2 Methods for increasing the ion permeability of contact lenses NOVARTIS AG (CH) 2014-11-11 US disclosed
US-8835525-B2 Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains NOVARTIS AG (CH) 2014-09-16 US disclosed
US-20140178595-A1 Method for Making Improved UV-Absorbing Ophthalmic Lenses NOVARTIS AG (CH) 2014-06-26 US disclosed
US-20140100291-A1 Actinically-Crosslinkable Siloxane-Containing Copolymers NOVARTIS AG (CH) 2014-04-10 US disclosed
EP-2705808-A2 Silicone hydrogel lenses with water-rich surfaces Novartis AG (CH) 2014-03-12 EP disclosed
US-8642712-B2 Actinically-crosslinkable siloxane-containing copolymers NOVARTIS AG (CH) 2014-02-04 US disclosed
US-20140005430-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2014-01-02 US disclosed
US-8557334-B2 Silicone hydrogel lens with a covalently attached coating NOVARTIS AG (CH) 2013-10-15 US disclosed
US-8557940-B2 Amphiphilic polysiloxane prepolymers and uses thereof NOVARTIS AG (CH) 2013-10-15 US disclosed
US-20130250234-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES NOVARTIS AG (CH) 2013-09-26 US disclosed
EP-2638878-A2 Silicone hydrogel lenses with water-rich surfaces Novartis AG (CH) 2013-09-18 EP disclosed
EP-2638879-A2 Silicone hydrogel lenses with water-rich surfaces Novartis AG (CH) 2013-09-18 EP disclosed
US-8480227-B2 Silicone hydrogel lenses with water-rich surfaces NOVARTIS AG (CH) 2013-07-09 US disclosed
EP-2461767-B1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES NOVARTIS AG (CH) 2013-05-08 EP disclosed
US-8431624-B2 Prepolymers suitable for making ultra-violet absorbing contact lenses NOVARTIS AG (CH) 2013-04-30 US disclosed
US-8383744-B2 Actinically-crosslinkable siloxane-containing copolymers NOVARTIS AG (CH) 2013-02-26 US disclosed
US-20120314185-A1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES ALCON INC. (CH) 2012-12-13 US disclosed
US-20120088844-A1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS ALCON INC. (CH) 2012-04-12 US disclosed
US-20120088843-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS ALCON INC. (CH) 2012-04-12 US disclosed
US-20120088861-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-04-12 US disclosed
US-20120026458-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC. (CH) 2012-02-02 US disclosed
US-20120029111-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-02-02 US disclosed
US-20110134387-A1 SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING ALCON INC. (CH) 2011-06-09 US disclosed
US-20110133350-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES ALCON INC. (CH) 2011-06-09 US disclosed
US-20110063567-A1 PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES ALCON INC. (CH) 2011-03-17 US disclosed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US disclosed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US disclosed
US-20100298446-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 KDM4E 1450/4885MAPK1 1115/4885HIF1A 138/4885
US-10268053-B2 UV/visible-absorbing vinylic monomers and uses thereof VCL, UACA, XRCC6 KDM4E 793/4885MAPK1 2363/4885HIF1A 817/4885
US-20170242275-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF UACA, VCL, CRYZ KDM4E 906/4885MAPK1 2110/4885HIF1A 720/4885
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 KDM4E 2968/4885MAPK1 3597/4885HIF1A 986/4885
US-20100298446-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ATRIP, ATR, MACF1 KDM4E 2683/4885MAPK1 3399/4885HIF1A 2207/4885
US-20140100291-A1 Actinically-Crosslinkable Siloxane-Containing Copolymers ATRIP, ATR, MACF1 KDM4E 2683/4885MAPK1 3399/4885HIF1A 2207/4885
US-20120088843-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS GFER, DRD1, SORD KDM4E 4206/4885MAPK1 4036/4885HIF1A 2142/4885
US-20120029111-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF PIGS, ELOVL1, HACD2 KDM4E 3801/4885MAPK1 4175/4885HIF1A 729/4885
US-10823983-B2 UV-absorbing vinylic monomers and uses thereof UACA, VCL, CRYZ KDM4E 906/4885MAPK1 2110/4885HIF1A 720/4885
US-20190179170-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF UACA, VCL, CRYZ KDM4E 906/4885MAPK1 2110/4885HIF1A 720/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 KDM4E 1841/4885MAPK1 2195/4885HIF1A 34/4885
US-20250387989-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES PHOSPHO1, MYOC, ASS1 KDM4E 3432/4885MAPK1 337/4885HIF1A 1101/4885
US-10254567-B2 UV-absorbing vinylic monomers and uses thereof UACA, VCL, CRYZ KDM4E 906/4885MAPK1 2110/4885HIF1A 720/4885
US-20120088844-A1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS HACD2, HACD3, PCNA KDM4E 3476/4885MAPK1 3316/4885HIF1A 1792/4885
US-20140350124-A1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS HACD2, HACD3, PCNA KDM4E 3476/4885MAPK1 3316/4885HIF1A 1792/4885
US-20170242274-A1 UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF VCL, UACA, XRCC6 KDM4E 793/4885MAPK1 2363/4885HIF1A 817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.