Sugi Predict

Sugi Predict / Compounds / SCHEMBL2476560

SCHEMBL2476560

SCHEMBL2476560

[C]1CCCc2nc3ccccc3nc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 5/20 0.39
▸ ACHE P22303 5/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ TSHR P16473 3/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ CACNB4 O00305 1/20 0.39
▸ CACNA1A O00555 1/20 0.39
▸ SLC22A2 O15244 1/20 0.39
▸ SLC22A1 O15245 1/20 0.39
▸ ABCC4 O15439 1/20 0.39
▸ CACNA1G O43497 1/20 0.39
▸ CACNG3 O60359 1/20 0.39
▸ CACNA1F O60840 1/20 0.39
▸ CACNA1H O95180 1/20 0.39
▸ APP P05067 1/20 0.39
▸ FABP1 P07148 1/20 0.39
▸ CHRM2 P08172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14572403 0.74 BCHE (0.53) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL2926573 0.74 KMT2A (0.56) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL3868709 0.73 ACHE (0.42) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL11870225 0.63 MAPT (0.50) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL9823209 0.61 HTT (0.47) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL25409087 0.61 MAPT (0.48) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL25409084 0.61 MAPT (0.48) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL26363970 0.61 MAPT (0.48) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL637593 0.61 KDM4E (0.39) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL1532144 0.60 BCHE (0.45) BCHEACHEALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 — — WO disclosed
EP-3632441-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND DAY ONE BIOPHARMACEUTICALS INC (US) 2024-07-17 — — EP disclosed
CN-118344346-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-16 — — CN disclosed
EP-3782986-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2024-07-10 — — EP disclosed
CN-118290408-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-05 — — CN disclosed
US-20240217957-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-04 — — US disclosed
CN-118271297-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-02 — — CN disclosed
CN-118271298-A Heterocyclic compounds and their use 武田药品工业株式会社 2024-07-02 — — CN disclosed
US-12024505-B2 Heterocyclic compounds useful as modulators of acetylcholine receptors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-02 — — US disclosed
WO-2024135652-A1 REISSERT-HENZE REACTION USING PHOSPHONIC ACID ANHYDRIDE AS ACTIVATOR ＡＧＣ株式会社 2024-06-27 — — WO disclosed
US-7183415-B2 Quinoline compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-27 — — US disclosed
US-20060223826-A1 Indole derivatives as somatostatin agonists or antagonists TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) 2006-10-05 — — US disclosed
US-20060128690-A1 Amine derivative TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-06-15 — — US disclosed
EP-1593667-A1 AMINE DERIVATIVE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 — — EP disclosed
US-20050245571-A1 Amine derivative TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-11-03 — — US disclosed
US-20050209213-A1 Quinoline compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-22 — — US disclosed
EP-1562898-A1 INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS Takeda Pharmaceutical Company Limited (JP) 2005-08-17 — — EP disclosed
EP-1447402-A1 QUINOLINE COMPOUND Takeda Chemical Industries, Ltd. (JP) 2004-08-18 — — EP disclosed
EP-1437351-A1 AMINE DERIVATIVE Takeda Chemical Industries, Ltd. (JP) 2004-07-14 — — EP disclosed
WO-2004046107-A1 INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-06-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223826-A1 Indole derivatives as somatostatin agonists or antagonists SSTR1, SSTR3, NPY1R BCHE 1369/4885ACHE 1512/4885ALDH1A1 2632/4885
US-20240217957-A1 HETEROCYCLIC COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NPY2R BCHE 1156/4885ACHE 2249/4885ALDH1A1 1679/4885
US-20060128690-A1 Amine derivative MC1R, MC2R, MC4R BCHE 3398/4885ACHE 3681/4885ALDH1A1 332/4885
US-12024505-B2 Heterocyclic compounds useful as modulators of acetylcholine receptors CHRM3, CHRNA1, CHRM5 BCHE 142/4885ACHE 28/4885ALDH1A1 1030/4885
US-20050245571-A1 Amine derivative NPY1R, SSTR1, SSTR5 BCHE 944/4885ACHE 1968/4885ALDH1A1 2688/4885
US-20050209213-A1 Quinoline compound MC1R, MC2R, TYR BCHE 2215/4885ACHE 2776/4885ALDH1A1 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.