SCHEMBL24767488

SCHEMBL24767488

CCc1ccc(C(OCCF)(c2ccccc2)c2ccc(CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.53
TP53 P04637 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HRH4 Q9H3N8 1/20 0.36
TK2 O00142 6/20 0.35
DUT P33316 1/20 0.35
TK1 P04183 1/20 0.35
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19020520 0.79 TP53 (0.48) KIF11TP53MEN1KMT2ATK1
SCHEMBL9204337 0.78 TP53 (0.52) KIF11TP53MEN1KMT2AMAPK1
SCHEMBL2348691 0.76 KIF11 (0.65) KIF11MEN1KMT2AHRH4TK2
SCHEMBL11275984 0.73 KIF11 (0.74) KIF11HRH4TK2DUTTK1
SCHEMBL19021001 0.73 LTA4H (0.46) KIF11KMT2ASMN1; SMN2
SCHEMBL11432250 0.73 MAPK1 (0.68) KIF11TP53MEN1KMT2AMAPK1
SCHEMBL18803716 0.72 KIF11 (0.55) KIF11MEN1KMT2AHRH4TK2
SCHEMBL23098272 0.72 TP53 (0.48) KIF11TP53MEN1KMT2ASMN1; SMN2
SCHEMBL3398385 0.71 KIF11 (0.59) KIF11HRH4TK2DUTTK1
SCHEMBL2492363 0.70 KIF11 (1.00) KIF11MEN1KMT2AHRH4TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022264069-A1 METHOD FOR PREPARING FLUOROPHORE- AND CHROMOPHORE-CONTAINING CONJUGATES FOR VISUAL DETECTION OF ANALYTE MOLECULES Sony Group Corporation (JP) 2022-12-22 WO disclosed