Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793807 | 0.84 | PRMT1 (0.57) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL31213036 | 0.83 | CA12 (0.59) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL2592774 | 0.83 | CA12 (0.59) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL9692785 | 0.81 | HTT (0.62) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL29171465 | 0.80 | KDM4E (0.57) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11355898 | 0.80 | KDM4E (0.44) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL7827414 | 0.79 | ALDH1A1 (0.53) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL27469088 | 0.79 | ALDH1A1 (0.59) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL7823115 | 0.79 | CA12 (0.59) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL16869458 | 0.79 | KDM4E (0.54) | KDM4ENPC1RAB9ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184632-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from aminopyrrole arene and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2024-06-14 | — | — | CN | claimed |
| US-20240262812-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2024-08-08 | — | — | US | disclosed |
| CN-115477626-B | N-substituted phenyl sulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118184632-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from aminopyrrole arene and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2024-06-14 | — | — | CN | disclosed |
| EP-4357338-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | Shanghai Leado Pharmatech Co. Ltd. (CN) | 2024-04-24 | — | — | EP | disclosed |
| CN-117529474-A | N-substituted phenyl sulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2022262657-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | 上海璃道医药科技有限公司 | 2022-12-22 | — | — | WO | disclosed |
| WO-2022262657-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | 上海璃道医药科技有限公司 | 2022-12-22 | — | — | WO | disclosed |
| CN-115477626-A | N-substituted phenylsulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2022-12-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262812-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | TRPV1, TRPA1, TRPV5 | KDM4E 2673/4885NPC1 1827/4885RAB9A 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.