Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016562 | 0.97 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL27493267 | 0.93 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL3963428 | 0.91 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL28852620 | 0.89 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNATDP1 | |
| SCHEMBL133636 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL8492777 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1LMNATDP1 | |
| SCHEMBL18673 | 0.87 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1LMNATDP1 | |
| SCHEMBL10031001 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| Benzyl Carbamate SCHEMBL11051966 | 0.87 | ALOX5 (0.49) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL8988940 | 0.87 | ALOX5 (0.49) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | PTGER1, PTGIS, PTGIR | ALDH1A1 875/4885MAPK1 567/4885L3MBTL1 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.