Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16419566 | 1.00 | LMNA (0.36) | LMNAALDH1A1MAPTTDP1CYP2C9 | |
| SCHEMBL30416055 | 0.88 | CTSA (0.35) | LMNAALDH1A1MAPTKMT2ACTSA | |
| SCHEMBL22924871 | 0.88 | CTSA (0.35) | LMNAALDH1A1MAPTKMT2ACTSA | |
| SCHEMBL21381662 | 0.85 | CTSA (0.34) | LMNAALDH1A1MAPTTDP1CYP2C9 | |
| SCHEMBL2580431 | 0.84 | ALDH1A1 (0.38) | LMNAALDH1A1MAPTTDP1CYP2C9 | |
| SCHEMBL16778254 | 0.83 | ALDH1A1 (0.40) | LMNAALDH1A1MAPTTDP1CYP2C9 | |
| SCHEMBL21381538 | 0.83 | AKR1C3 (0.37) | LMNAALDH1A1TDP1CYP2C9CYP3A4 | |
| SCHEMBL30556962 | 0.74 | MAPK1 (0.39) | LMNAALDH1A1MAPTKMT2ACTSA | |
| SCHEMBL26122997 | 0.74 | MAPK1 (0.39) | LMNAALDH1A1MAPTKMT2ACTSA | |
| SCHEMBL21381413 | 0.74 | CTSA (0.43) | LMNAALDH1A1MAPTCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630515-B2 | Small molecule prostagladin transport inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2026-05-19 | — | — | US | disclosed |
| EP-4054608-B1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
| EP-4054608-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | Albert Einstein College of Medicine (US) | 2022-09-14 | — | — | EP | disclosed |
| US-20150031674-A1 | SERINE/THREONINE KINASE INHIBITORS | GENENTECH, INC. (US) | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031674-A1 | SERINE/THREONINE KINASE INHIBITORS | PAK1, AKT1, RB1 | LMNA 2523/4885ALDH1A1 2413/4885MAPT 1138/4885 |
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | PTGER1, PTGIS, PTGIR | LMNA 2850/4885ALDH1A1 875/4885MAPT 3079/4885 |
| US-12630515-B2 | Small molecule prostagladin transport inhibitors | PTGER1, PTGS1, PTGIR | LMNA 2813/4885ALDH1A1 1715/4885MAPT 4183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.