SCHEMBL24769728

SCHEMBL24769728

Nc1ccc(-n2cnnn2)cc1N

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 7/20 0.58
MAPT P10636 2/20 0.53
F2 P00734 1/20 0.53
KCNJ1 P48048 3/20 0.50
LMNA P02545 2/20 0.49
ALDH1A1 P00352 3/20 0.49
HTT P42858 1/20 0.49
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
POLB P06746 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22637227 0.84 NOTUM (0.53) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL428990 0.84 NOTUM (0.53) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL10463551 0.84 ALDH1A1 (0.57) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL24073776 0.84 NOTUM (0.53) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL24073780 0.80 NOTUM (0.49) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL221145 0.80 ALDH1A1 (0.56) NOTUMMAPTF2LMNAALDH1A1
SCHEMBL12615985 0.79 NOTUM (0.78) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL24073374 0.79 NOTUM (0.47) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL1163779 0.78 NOTUM (0.64) NOTUMMAPTF2KCNJ1LMNA
SCHEMBL22636960 0.77 MAPT (0.57) NOTUMMAPTF2KCNJ1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022202414-A1 PROTECTIVE TAPE, SEMICONDUCTOR PROTECTIVE TAPE, AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE 積水化学工業株式会社 2022-09-29 WO disclosed