Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24768598 | 0.74 | NPC1 (0.56) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL513805 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL24769832 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL38665488 | 0.72 | GAA (0.70) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10025209 | 0.70 | SREBF2 (0.54) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL8483276 | 0.70 | HIF1A (0.46) | ALDH1A1SMN1; SMN2MAPTMEN1MAPK1 | |
| SCHEMBL24769834 | 0.69 | GAA (0.56) | KDM4EALDH1A1MAPTMEN1MAPK1 | |
| SCHEMBL24769826 | 0.69 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL17742732 | 0.67 | HDAC1 (0.60) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2083581 | 0.67 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630515-B2 | Small molecule prostagladin transport inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2026-05-19 | — | — | US | disclosed |
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | PTGER1, PTGIS, PTGIR | KDM4E 4081/4885ALDH1A1 875/4885SMN1; SMN2 3813/4885 |
| US-12630515-B2 | Small molecule prostagladin transport inhibitors | PTGER1, PTGS1, PTGIR | KDM4E 4133/4885ALDH1A1 1715/4885SMN1; SMN2 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.