Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173049 | 0.87 | POLB (0.43) | POLBALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1387756 | 0.83 | ALDH1A1 (0.52) | POLBALDH1A1HPGDHTTSMN1; SMN2 | |
| Iodide SCHEMBL11445679 | 0.82 | ALDH1A1 (0.42) | POLBALDH1A1HPGDSMN1; SMN2TSHR | |
| Bromide SCHEMBL11804203 | 0.81 | ALDH1A1 (0.51) | POLBALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2286441 | 0.81 | ALDH1A1 (0.58) | POLBALDH1A1HPGDHTTSMN1; SMN2 | |
| Iodide SCHEMBL11170910 | 0.80 | GAA (0.52) | POLBALDH1A1SMN1; SMN2TSHRPKM | |
| Iodide SCHEMBL11215603 | 0.79 | TDP1 (0.41) | POLBALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL1185416 | 0.78 | ALDH1A1 (0.60) | POLBALDH1A1HPGDHTTSMN1; SMN2 | |
| Iodide SCHEMBL11166944 | 0.78 | HPGD (0.42) | POLBALDH1A1HPGDSMN1; SMN2PKM | |
| Iodide SCHEMBL11158727 | 0.77 | CYP19A1 (0.46) | POLBALDH1A1PKMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | PTGER1, PTGIS, PTGIR | POLB 4612/4885ALDH1A1 875/4885HPGD 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.