Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24768947 | 0.82 | MAPT (0.44) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL21620372 | 0.81 | RAB9A (0.49) | HSD17B10MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL21616549 | 0.81 | RAB9A (0.49) | HSD17B10MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL21620281 | 0.79 | GFER (0.46) | HSD17B10MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL23355955 | 0.79 | GFER (0.46) | HSD17B10MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL14784211 | 0.74 | MAPT (0.50) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL14784212 | 0.74 | MAPT (0.50) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL11188067 | 0.73 | MAPT (0.38) | MAPT | |
| SCHEMBL9328922 | 0.72 | NPC1 (0.42) | GABRA5GABRB2HSD17B10MAPTALDH1A1 | |
| SCHEMBL4400464 | 0.70 | MAPT (0.53) | GABRA5GABRB2HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220400678-A1 | OXIME ETHER COMPOUND AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220400678-A1 | OXIME ETHER COMPOUND AND APPLICATION THEREOF | CYP2E1, GALE, OGFOD1 | GABRA5 4267/4885GABRB2 4272/4885HSD17B10 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.