SCHEMBL24769896

SCHEMBL24769896

Cn1c(=O)[nH]c(=O)c2[nH]c(BF)nc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
GAA P10253 5/20 0.44
MAPK1 P28482 3/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
XBP1 P17861 1/20 0.44
ATM Q13315 1/20 0.44
KDM4E B2RXH2 3/20 0.43
CHRNB2 P17787 1/20 0.41
ADRA1D P25100 1/20 0.41
HTR1E P28566 1/20 0.41
CHRNA3 P32297 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRK1 P41145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24769374 0.77 POLB (0.53) ALDH1A1MAPK1KMT2ASMN1; SMN2NPSR1
SCHEMBL387339 0.75 ALDH1A1 (0.54) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL1241218 0.74 ALDH1A1 (0.49) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL3563144 0.74 ALDH1A1 (0.49) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL10309249 0.74 ALDH1A1 (0.49) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL6890038 0.74 CHRNB2 (0.53) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL18343921 0.74 ALDH1A1 (0.49) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL12782625 0.73 ALDH1A1 (0.46) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL10309259 0.71 ALDH1A1 (0.61) ALDH1A1GAAMAPK1MAPTKMT2A
SCHEMBL16870007 0.70 CHRNB2 (0.57) ALDH1A1GAAMAPK1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022262820-A1 GROUP OF IMB-C5 SERIES COMPOUNDS HAVING ANTI-CORONAVIRUS ACTIVITY AND APPLICATION THEREOF 中国医学科学院医药生物技术研究所 2022-12-22 WO disclosed