Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27209980 | 0.75 | CTSL (0.39) | CTSLCTSBCTSKEPHX2BCHE | |
| SCHEMBL1273271 | 0.73 | MMP1 (0.42) | EPHX2OPRM1OPRL1NPC1RAB9A | |
| SCHEMBL1272784 | 0.73 | MMP1 (0.42) | EPHX2OPRM1OPRL1NPC1RAB9A | |
| SCHEMBL27223928 | 0.72 | CTSL (0.41) | CTSLCTSBCTSKEPHX2BCHE | |
| SCHEMBL27223273 | 0.70 | CTSL (0.41) | CTSLCTSBCTSKEPHX2BCHE | |
| SCHEMBL24622152 | 0.70 | ABCB1 (0.41) | CTSLCTSBCTSKCHRM3EPHX2 | |
| SCHEMBL21996508 | 0.70 | ABCB1 (0.41) | CTSLCTSBCTSKCHRM3EPHX2 | |
| SCHEMBL22047128 | 0.70 | ABCB1 (0.41) | CTSLCTSBCTSKCHRM3OPRM1 | |
| SCHEMBL5151803 | 0.70 | ABCB1 (0.41) | CTSLCTSBCTSKCHRM3EPHX2 | |
| SCHEMBL21996534 | 0.69 | ABCB1 (0.41) | CTSLCTSBCTSKCHRM3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |