Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272784 | 1.00 | MMP1 (0.42) | MMP1HPGDPPIDOPRL1RIPK1 | |
| SCHEMBL1273336 | 0.83 | HPGD (0.46) | HPGDOPRL1RIPK1SLC6A4OPRM1 | |
| SCHEMBL3849116 | 0.79 | MEN1 (0.39) | SMN1; SMN2POLBMEN1KMT2ATSHR | |
| SCHEMBL17505973 | 0.75 | FPR2 (0.40) | HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL6508899 | 0.74 | OPRL1 (0.47) | HPGDOPRL1RIPK1OPRM1SMN1; SMN2 | |
| SCHEMBL5173018 | 0.74 | OPRL1 (0.47) | HPGDOPRL1RIPK1OPRM1SMN1; SMN2 | |
| SCHEMBL2477093 | 0.73 | CTSL (0.36) | OPRL1OPRM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16402974 | 0.71 | GRIN2B (0.36) | MMP1MEN1KMT2A | |
| SCHEMBL16403229 | 0.70 | ALDH1A1 (0.35) | MMP1MEN1KMT2A | |
| SCHEMBL16400539 | 0.69 | GRIN2B (0.35) | MMP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | BIRC5, XIAP, BIRC2 | MMP1 3311/4885HPGD 2842/4885PPID 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.