Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20592727 | 0.81 | POLQ (0.44) | PDK2GABRA1GABRB2POLQALDH1A1 | |
| SCHEMBL2393250 | 0.76 | AKR1C3 (0.46) | PDK2AKR1C3AKR1C2ALDH1A1HPGD | |
| SCHEMBL5530171 | 0.75 | GABRA1 (0.42) | KAT6AGABRA1GABRB2POLQPTGS2 | |
| SCHEMBL27176597 | 0.75 | GABRA1 (0.42) | PDK2GABRA1GABRB2PTGS2P2RX7 | |
| SCHEMBL5415312 | 0.73 | GABRA1 (0.46) | GABRA1GABRB2POLQEPHX2LMNA | |
| SCHEMBL8462696 | 0.73 | PDCD1 (0.46) | PDK2KAT6AGABRA1GABRB2PTPN5 | |
| SCHEMBL17039134 | 0.73 | CYP2D6 (0.39) | PDK2KAT6AGABRA1GABRB2ALDH1A1 | |
| SCHEMBL25019428 | 0.72 | GABRA1 (0.45) | PDK2KAT6AGABRA1GABRB2LMNA | |
| SCHEMBL2397461 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2PPARGKMT2A | |
| SCHEMBL22827470 | 0.71 | GABRA1 (0.45) | PDK2KAT6AGABRA1GABRB2POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374790-A1 | BIPHENYLACETAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |