Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964988 | 0.84 | GABRA1 (0.45) | GABRA1GABRB2RIPK1POLQCLCN2 | |
| SCHEMBL5576461 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2CTSSMEN1KMT2A | |
| SCHEMBL2477656 | 0.75 | PDK2 (0.40) | GABRA1GABRB2KAT6AP2RX7POLQ | |
| SCHEMBL6558804 | 0.75 | GABRA1 (0.39) | GABRA1GABRB2RIPK1POLQCLCN2 | |
| SCHEMBL1772317 | 0.75 | RIPK1 (0.43) | RIPK1MEN1MAPTKMT2A | |
| SCHEMBL5415312 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2P2RX7POLQCTSS | |
| SCHEMBL14039398 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2KAT6ARIPK1P2RX7 | |
| SCHEMBL25019428 | 0.73 | GABRA1 (0.45) | GABRA1GABRB2KAT6ARIPK1P2RX7 | |
| SCHEMBL9903207 | 0.73 | POLB (0.36) | MEN1KMT2A | |
| SCHEMBL22827470 | 0.72 | GABRA1 (0.45) | GABRA1GABRB2KAT6ARIPK1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | PEES KLAUS-JUERGEN | 2007-09-06 | — | — | US | disclosed |
| US-7230104-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| EP-1577312-A1 | Triazolopyrimidine intermediate compounds for fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-21 | — | — | EP | disclosed |
| US-6943252-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-13 | — | — | US | disclosed |
| EP-1289963-B1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2004-07-29 | — | — | US | disclosed |
| US-6632821-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, NOX5 | GABRA1 1269/4885GABRB2 2048/4885KAT6A 3496/4885 |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, CYP3A5 | GABRA1 1135/4885GABRB2 1788/4885KAT6A 3817/4885 |
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | CBR3, NOX5, CBR1 | GABRA1 1419/4885GABRB2 2117/4885KAT6A 3672/4885 |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR1, CBR3, ARSA | GABRA1 656/4885GABRB2 1181/4885KAT6A 3157/4885 |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, NOX5, CBR1 | GABRA1 974/4885GABRB2 1498/4885KAT6A 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.