Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | PLG | P00747 | 5/20 | 0.41 |
| ▸ | PLAT | P00750 | 5/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324841 | 1.00 | KDM4E (0.50) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL28022272 | 0.83 | SELL (0.54) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL27718146 | 0.78 | PRSS1 (0.38) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL23685779 | 0.78 | KDM4E (0.50) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL23062880 | 0.74 | ACHE (0.54) | KDM4EGAAALDH1A1LMNAMAPT | |
| Methylamine SCHEMBL18641326 | 0.73 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL29670017 | 0.73 | ALDH1A1 (0.48) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL28413744 | 0.73 | ALDH1A1 (0.48) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL36529 | 0.72 | ALDH1A1 (0.65) | KDM4EGAAALDH1A1LMNAMAPT | |
| SCHEMBL27800318 | 0.72 | ALDH1A1 (0.65) | KDM4EGAAALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370438-A1 | IMIDAZO [1,2A]PYRIDINE DERIVATIVES, THEIR USE AS S1P1 AGONISTS AND METHODS FOR THEIR PRODUCTION | Exelixis, Inc. (US) | 2011-10-05 | — | — | EP | disclosed |