Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477700 | 1.00 | EPHX2 (0.41) | EPHX2PPARGFFAR1CYP1A2CYP3A4 | |
| SCHEMBL2480037 | 0.87 | EPHX2 (0.32) | EPHX2SMN1; SMN2 | |
| SCHEMBL2480035 | 0.87 | EPHX2 (0.32) | EPHX2SMN1; SMN2 | |
| SCHEMBL2473954 | 0.87 | ALDH1A1 (0.33) | EPHX2TDP1 | |
| SCHEMBL2473955 | 0.87 | ALDH1A1 (0.33) | EPHX2TDP1 | |
| SCHEMBL2673318 | 0.83 | SLC6A2 (0.36) | FFAR1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL2673314 | 0.83 | SLC6A2 (0.36) | FFAR1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL2673320 | 0.83 | SLC6A2 (0.36) | FFAR1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL2480356 | 0.81 | MGLL (0.38) | TDP1 | |
| SCHEMBL2480359 | 0.81 | MGLL (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |