Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 8/20 | 0.36 |
| ▸ | SDC2 | P34741 | 8/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23128864 | 0.88 | MAPT (0.36) | SDCBPSDC2THRBGAAKDM4E | |
| SCHEMBL25571489 | 0.86 | MAPT (0.36) | SDCBPSDC2THRBGAAKDM4E | |
| SCHEMBL24421373 | 0.83 | SDCBP (0.42) | SDCBPSDC2THRBGAAKDM4E | |
| SCHEMBL24421543 | 0.83 | SDCBP (0.50) | SDCBPSDC2THRBGAAKDM4E | |
| SCHEMBL24294534 | 0.83 | THRB (0.43) | THRBGAAKDM4EALOX15POLB | |
| SCHEMBL24294314 | 0.83 | THRB (0.43) | THRBGAAKDM4EALOX15POLB | |
| SCHEMBL24778609 | 0.81 | SDCBP (0.35) | SDCBPSDC2THRBGAAPOLB | |
| SCHEMBL24421564 | 0.81 | SDCBP (0.42) | SDCBPSDC2THRBKDM4EALOX15 | |
| SCHEMBL24421581 | 0.80 | THRB (0.41) | SDCBPSDC2THRBGAAKDM4E | |
| SCHEMBL25032020 | 0.80 | ALOX15 (0.40) | SDCBPSDC2THRBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266258-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4 | ARVINAS OPERATIONS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |