SCHEMBL24780765

SCHEMBL24780765

O=c1cnn(Cc2cc(Cl)c(Oc3cc(F)c(F)c(F)c3)c(Cl)c2)c(=O)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.43
THRA P10827 4/20 0.43
NPBWR1 P48145 12/20 0.39
MCHR1 Q99705 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24780755 0.85 NPBWR1 (0.53) THRBTHRANPBWR1MCHR1
SCHEMBL24781768 0.84 THRB (0.47) THRBTHRANPBWR1MCHR1
SCHEMBL24781783 0.84 THRA (0.35) THRBTHRANPBWR1
SCHEMBL24780817 0.84 NPBWR1 (0.41) THRBTHRANPBWR1MCHR1
SCHEMBL24781772 0.84 NPBWR1 (0.51) THRBTHRANPBWR1MCHR1
SCHEMBL24781765 0.84 NPBWR1 (0.54) THRBTHRANPBWR1MCHR1
SCHEMBL24781767 0.81 NPBWR1 (0.58) THRBTHRANPBWR1MCHR1
SCHEMBL24781771 0.81 THRB (0.43) THRBTHRANPBWR1MCHR1
SCHEMBL24780819 0.81 NPBWR1 (0.41) NPBWR1MCHR1
SCHEMBL24780759 0.80 NPBWR1 (0.57) THRBTHRANPBWR1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022262821-A1 DICLAZURIL DERIVATIVE AND APPLICATION THEREOF, AND FUNGICIDE FOR COMBATING PLANT DISEASES 江苏中旗科技股份有限公司 2022-12-22 WO disclosed