⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL175940 | 1.00 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL8568063 | 1.00 | SLC7A5 (1.00) | — | |
| D-Leucine SCHEMBL9449950 | 1.00 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL20362356 | 1.00 | — | — | |
| D-Leucine SCHEMBL42012 | 1.00 | — | — | |
| Leucine SCHEMBL25241602 | 1.00 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL8568060 | 1.00 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL331557 | 1.00 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL2478164 | 1.00 | SLC7A5 (1.00) | — | |
| D-Leucine SCHEMBL9100148 | 1.00 | SLC7A5 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 625351 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7053724-B2 | — | バイエル・ヘルスケア・エルエルシー | 2022-04-12 | — | — | JP | claimed |
| US-9975935-B2 | NEIL3 peptides and vaccines including the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-9976126-B2 | Modified glycine oxidase | AJINOMOTO CO., INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-9974851-B2 | Human rotavirus vaccine strains and diagnostics | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-22 | — | — | US | claimed |
| US-9976074-B2 | Self-suspending proppant particulates using canola protein-based hydrogel | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9974833-B2 | Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid homeostasis in a subject having pregnancy intrahepatic cholestasis | NGM BIOPHARMACEUTICALS, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9975932-B2 | Variants of group 5 allergens of the true grasses having reduced allergeneity due to mutagenesis of proline residues | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | claimed |
| US-20180133185-A1 | Compositions and Methods for the Improvement of Memory | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2018-05-17 | — | — | US | claimed |
| US-20180135012-A1 | MEMBRANE-RECEIVER COMPLEX THERAPEUTICS | FLAGSHIP PIONEERING, INC. | 2018-05-17 | — | — | US | claimed |
| US-20180135086-A1 | MICROORGANISM PRODUCING O-ACETYL-HOMOSERINE, AND METHOD FOR PRODUCING O-ACETYL-HOMOSERINE BY USING SAME | CJ CHEILJEDANG CORPORATION (KR) | 2018-05-17 | — | — | US | claimed |
| US-3972776-A | Preparation of protein membranes containing microbial cells | RESEARCH CORPORATION (US) | 1976-08-03 | — | — | US | claimed |
| US-3960942-A | Leucine isoleucine separation | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS (CH) | 1976-06-01 | — | — | US | claimed |
| US-3953416-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same | FOLKERS KARL | 1976-04-27 | — | — | US | claimed |
| US-3950529-A | NUTRIENT SOLUTION FOR INTRAVENOUS ADMINISTRATION | MASSACHUSETTS GENERAL HOSPITAL (US) | 1976-04-13 | — | — | US | claimed |
| US-3950513-A | NONTOXIC AMINO ACID | NOVO TERAPEUTISK LABORATORIUM A/S (DK) | 1976-04-13 | — | — | US | claimed |
| US-3947589-A | Fungicidal methods employing amino acid derivatives | RIKAGAKU KENKYUSHO (JA) | 1976-03-30 | — | — | US | claimed |
| US-3943241-A | Cariostatic composition | GENERAL MILLS, INC. (US) | 1976-03-09 | — | — | US | claimed |
| US-3943038-A | Method for producing amino acids by culturing hydrogen-oxidizing bacteria | AJINOMOTO CO., INC. (JA) | 1976-03-09 | — | — | US | claimed |
| US-3936469-A | Process for preparing N-carboxylic anhydrides of amino acids | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | claimed |
| US-3931141-A | Novel heptapeptides having gastrin activity | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | claimed |