Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13081023 | 0.83 | ACACB (0.41) | CCR2L3MBTL1CA1CA2 | |
| SCHEMBL13126736 | 0.81 | CCR2 (0.47) | CCR2L3MBTL1CA1MMP8 | |
| SCHEMBL12308382 | 0.78 | MMP8 (0.39) | CA1CA2MMP8 | |
| SCHEMBL13126734 | 0.78 | CA1 (0.37) | CCR2L3MBTL1CA1CA2 | |
| SCHEMBL13126738 | 0.78 | CCR2 (0.41) | CCR2L3MBTL1CA1MMP8 | |
| SCHEMBL14293838 | 0.77 | ACACB (0.37) | CCR2CA1CA2 | |
| SCHEMBL5154430 | 0.76 | TDP1 (0.46) | CCR2CA1CA2 | |
| SCHEMBL17447510 | 0.75 | CCR2 (0.40) | CCR2L3MBTL1 | |
| SCHEMBL17447468 | 0.73 | CCR2 (0.39) | CCR2L3MBTL1ANPEPRNPEPDNPEP | |
| SCHEMBL17447513 | 0.73 | CTSS (0.40) | CCR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |