Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174962 | 0.84 | MCHR1 (0.56) | NOTUMMCHR1DRD2DDB1CRBN | |
| SCHEMBL27752850 | 0.84 | MCHR1 (0.56) | NOTUMMCHR1DRD2DDB1CRBN | |
| SCHEMBL16719407 | 0.84 | MCHR1 (0.56) | NOTUMMCHR1DRD2DDB1CRBN | |
| SCHEMBL5543887 | 0.80 | ME3 (0.48) | DRD2DRD3HRH1L3MBTL1 | |
| SCHEMBL5543880 | 0.80 | HRH1 (0.42) | MCHR1DRD2DRD3HRH1CYP3A4 | |
| SCHEMBL5540300 | 0.80 | HRH1 (0.42) | MCHR1DRD2DRD3HRH1CYP3A4 | |
| SCHEMBL21447979 | 0.77 | L3MBTL3 (0.52) | NOTUMMCHR1DRD2DRD3CYP3A4 | |
| SCHEMBL10563190 | 0.75 | OPRM1 (0.44) | DRD2DRD3HRH1 | |
| SCHEMBL901151 | 0.75 | HTR2A (0.54) | DRD3HRH1 | |
| Hydrochloric Acid SCHEMBL27659479 | 0.75 | L3MBTL3 (0.50) | NOTUMMCHR1DRD2DRD3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |