Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784205 | 0.91 | KMT2A (0.49) | GLAALDH1A1THRBKMT2ATHRA | |
| SCHEMBL15759108 | 0.84 | ALDH1A1 (0.44) | ALDH1A1THRBTHRAPAOXSIGMAR1 | |
| SCHEMBL7003667 | 0.84 | GLA (0.44) | GLAALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL11243579 | 0.81 | THRB (0.45) | ALDH1A1THRBKMT2ATHRAMEN1 | |
| Hydrochloric Acid SCHEMBL11244737 | 0.79 | THRB (0.44) | GLAALDH1A1THRBKMT2ATHRA | |
| SCHEMBL21816623 | 0.78 | LMNA (0.51) | ALDH1A1THRBKMT2ATHRALMNA | |
| SCHEMBL11446827 | 0.78 | SIGMAR1 (0.49) | ALDH1A1SMN1; SMN2CYP1A2MAPK1SIGMAR1 | |
| SCHEMBL10254267 | 0.78 | GLA (0.53) | GLAALDH1A1THRBKMT2ATHRA | |
| SCHEMBL26579714 | 0.77 | GLA (0.52) | GLAALDH1A1KMT2AMAPTRAB9A | |
| SCHEMBL259485 | 0.77 | GLA (0.47) | GLAALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383804-A | The crystal form of neurotrophin simulated compound and its salt | 特罗菲克斯制药股份有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-104761515-B | The crystal formation of neurotrophin simulated compound and its salt | 特罗菲克斯制药股份有限公司 | 2018-03-09 | — | — | CN | disclosed |
| WO-2010102212-A2 | NEUROTROPHIN MIMETICS AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-09-10 | — | — | WO | disclosed |