Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11244737 | 0.99 | THRB (0.44) | THRBTHRAEPHX2ALDH1A1MEN1 | |
| SCHEMBL3673101 | 0.81 | GLA (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2811457 | 0.81 | GLA (0.44) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL21120552 | 0.80 | MAPK1 (0.44) | THRBTHRAALDH1A1SIGMAR1 | |
| SCHEMBL20333442 | 0.80 | MAPK1 (0.44) | THRBTHRAALDH1A1SIGMAR1 | |
| SCHEMBL11251853 | 0.79 | HRH2 (0.44) | THRBEPHX2SIGMAR1 | |
| SCHEMBL11253929 | 0.78 | HTR1A (0.49) | THRBEPHX2ALDH1A1SIGMAR1 | |
| SCHEMBL21816623 | 0.77 | LMNA (0.51) | THRBTHRAALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL24784205 | 0.77 | KMT2A (0.49) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL20625249 | 0.77 | EPHX2 (0.62) | EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008696-A1 | Basically substituted urea compounds, process for producing the same and pharmaceutical compositions containing the same | Asta-Werke Aktiengesellschaft Chemische Fabrik (DE) | 1980-03-19 | — | — | EP | claimed |
| EP-0008696-B1 | BASICALLY SUBSTITUTED UREA COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Asta-Werke Aktiengesellschaft Chemische Fabrik (DE) | 1982-12-15 | — | — | EP | disclosed |
| US-4239761-A | VIRICIDES | ASTA-WERKE AKTIENGESELLSCHAFT, CHEMISCHE FABRIK (DE) | 1980-12-16 | — | — | US | disclosed |
| EP-0008696-A1 | Basically substituted urea compounds, process for producing the same and pharmaceutical compositions containing the same | Asta-Werke Aktiengesellschaft Chemische Fabrik (DE) | 1980-03-19 | — | — | EP | disclosed |