Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783640 | 1.00 | ALOX5 (0.38) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL3456115 | 0.81 | USP2 (0.38) | CYP3A4MAPTMAPK1 | |
| SCHEMBL9308823 | 0.77 | TBXA2R (0.39) | ALOX5CYP2C9TBXA2R | |
| SCHEMBL14666117 | 0.76 | USP2 (0.39) | CYP3A4CYP2D6MAPTCYP2C9MAPK1 | |
| SCHEMBL9309778 | 0.75 | TBXA2R (0.38) | CYP2C9TBXA2R | |
| SCHEMBL24784363 | 0.71 | LMNA (0.42) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL24783641 | 0.71 | LMNA (0.42) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL11098325 | 0.68 | LMNA (0.40) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL22172495 | 0.67 | LMNA (0.42) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL1242706 | 0.66 | TNKS2 (0.35) | ALOX5LMNAPGRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300987-A1 | TRAP1 INHIBITOR AND USE THEREOF | UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) | 2024-09-12 | — | — | US | disclosed |
| EP-4357351-A1 | TRAP1 INHIBITOR AND USE THEREOF | Smartin Bio Inc. (KR) | 2024-04-24 | — | — | EP | disclosed |
| CN-117769559-A | TRAP1 inhibitors and uses thereof | 斯玛特恩生物公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2022265178-A1 | TRAP1 INHIBITOR AND USE THEREOF | 주식회사 스마틴바이오 | 2022-12-22 | — | — | WO | disclosed |
| WO-2022265178-A1 | TRAP1 INHIBITOR AND USE THEREOF | 주식회사 스마틴바이오 | 2022-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300987-A1 | TRAP1 INHIBITOR AND USE THEREOF | TRAP1, PPP1R7, PPP1R15A | ALOX5 4762/4885LMNA 3772/4885PGR 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.