Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681591 | 0.77 | PRCP (0.47) | PRCP | |
| SCHEMBL50587 | 0.77 | PRCP (0.47) | PRCP | |
| SCHEMBL6443468 | 0.75 | PRCP (0.33) | PRCPGAA | |
| SCHEMBL19542124 | 0.75 | ALOX15 (0.48) | ALOX15HSD17B10GAANPSR1HSD17B3 | |
| SCHEMBL14084313 | 0.75 | ALOX15 (0.48) | ALOX15HSD17B10PRCPGAANPSR1 | |
| Tetrafluoroethylene SCHEMBL6451837 | 0.69 | PRCP (0.41) | PRCP | |
| Styrene SCHEMBL28135034 | 0.68 | ALDH1A1 (0.50) | PRCP | |
| SCHEMBL4253259 | 0.67 | ALOX15 (0.47) | ALOX15HSD17B10GAANPSR1HSD17B3 | |
| SCHEMBL20829562 | 0.67 | ALOX15 (0.47) | ALOX15HSD17B10GAANPSR1HSD17B3 | |
| SCHEMBL18761542 | 0.67 | ALOX15 (0.47) | ALOX15HSD17B10GAANPSR1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673865-B2 | Cyclooctynes for click chemistry | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220402876-A1 | CYCLOOCTYNES FOR CLICK CHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402876-A1 | CYCLOOCTYNES FOR CLICK CHEMISTRY | CBR3, CYCS, APOBEC3C | ALOX15 200/4885HSD17B10 1158/4885PRCP 3325/4885 |
| US-11673865-B2 | Cyclooctynes for click chemistry | CBR3, CYCS, APOBEC3C | ALOX15 200/4885HSD17B10 1158/4885PRCP 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.