Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681904 | 1.00 | TLR2 (0.40) | TLR2NAPEPLDTLR4LMNAALDH1A1 | |
| SCHEMBL24787485 | 0.92 | DNM1 (0.33) | TLR2ALDH1A1DNM1MAPT | |
| SCHEMBL24787486 | 0.90 | DNM1 (0.31) | TLR2DNM1 | |
| SCHEMBL25681831 | 0.86 | FAAH (0.36) | ALDH1A1DNM1HSP90AA1 | |
| SCHEMBL25682074 | 0.85 | DNM1 (0.35) | ALDH1A1DNM1 | |
| SCHEMBL19681644 | 0.84 | MEN1 (0.32) | LMNADNM1MAPTMEN1KMT2A | |
| SCHEMBL25681951 | 0.82 | DNM1 (0.42) | ALDH1A1DNM1 | |
| SCHEMBL19681645 | 0.78 | FAAH (0.35) | LMNADNM1MEN1KMT2AHSP90AA1 | |
| SCHEMBL21965331 | 0.77 | DNM1 (0.34) | LMNADNM1MEN1KMT2A | |
| SCHEMBL15057129 | 0.77 | FAAH (0.49) | LMNAALDH1A1DNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261185-A1 | POLYNUCLEOTIDE COMPOSITIONS, RELATED FORMULATIONS, AND METHODS OF USE THEREOF | RECODE THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |