Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24787485 | 0.92 | DNM1 (0.33) | DNM1MAPTEPHX2TRPV1 | |
| SCHEMBL19681645 | 0.87 | FAAH (0.35) | MEN1LMNAPOLBGRK2KMT2A | |
| SCHEMBL21965331 | 0.86 | DNM1 (0.34) | MEN1LMNAPOLBGRK2KMT2A | |
| SCHEMBL19681591 | 0.85 | BBOX1 (0.39) | MEN1LMNAPOLBGRK2KMT2A | |
| SCHEMBL25681904 | 0.84 | TLR2 (0.40) | MEN1LMNAKMT2ADNM1MAPT | |
| SCHEMBL24787484 | 0.84 | TLR2 (0.40) | MEN1LMNAKMT2ADNM1MAPT | |
| SCHEMBL24787486 | 0.83 | DNM1 (0.31) | DNM1 | |
| SCHEMBL19681581 | 0.79 | ADRA1D (0.37) | MAPTADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL25681831 | 0.78 | FAAH (0.36) | L3MBTL1DNM1EPHX2 | |
| SCHEMBL30511241 | 0.78 | BBOX1 (0.45) | DNM1ADRA1DPTAFRHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685710-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-27 | — | — | US | disclosed |
| US-20210395192-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-12-23 | — | — | US | disclosed |
| US-10562849-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-02-18 | — | — | US | disclosed |
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | MEN1 2129/4885LMNA 2073/4885POLB 1641/4885 |
| US-10562849-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | ABHD16A, AARS1, CFTR | MEN1 2129/4885LMNA 2073/4885POLB 1641/4885 |
| US-11685710-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | ABHD16A, AARS1, CFTR | MEN1 2129/4885LMNA 2073/4885POLB 1641/4885 |
| US-20210395192-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | MEN1 2129/4885LMNA 2073/4885POLB 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.