Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807536 | 0.84 | ACVRL1 (0.32) | TMPRSS2 | |
| SCHEMBL18666834 | 0.84 | ACVRL1 (0.32) | TMPRSS2 | |
| SCHEMBL23047661 | 0.84 | ACVRL1 (0.32) | TMPRSS2 | |
| SCHEMBL24791284 | 0.72 | TMPRSS2 (0.38) | TMPRSS2CHRNA7HTR3A | |
| SCHEMBL20834954 | 0.72 | MAP4K4 (0.37) | MAP4K4CHRNA7HTR3AEGFRKDR | |
| SCHEMBL24789410 | 0.72 | RIPK1 (0.32) | TMPRSS2 | |
| SCHEMBL24106482 | 0.69 | TMPRSS2 (0.67) | TMPRSS2MAP4K4 | |
| SCHEMBL24789459 | 0.69 | RIPK1 (0.33) | — | |
| SCHEMBL25914642 | 0.68 | TMPRSS2 (0.30) | TMPRSS2 | |
| SCHEMBL4971072 | 0.68 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |