Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807536 | 1.00 | ACVRL1 (0.32) | ACVRL1PIK3CDPOLRMTRIPK1TMPRSS2 | |
| SCHEMBL18666834 | 1.00 | ACVRL1 (0.32) | ACVRL1PIK3CDPOLRMTRIPK1TMPRSS2 | |
| SCHEMBL24790993 | 0.84 | TMPRSS2 (0.36) | TMPRSS2 | |
| SCHEMBL24789459 | 0.83 | RIPK1 (0.33) | PIK3CDPOLRMTRIPK1 | |
| SCHEMBL4971072 | 0.82 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL24789410 | 0.82 | RIPK1 (0.32) | ACVRL1RIPK1TMPRSS2 | |
| SCHEMBL4970753 | 0.81 | TMPRSS2 (0.36) | ACVRL1PIK3CDTMPRSS2TNK2 | |
| SCHEMBL10142076 | 0.81 | TMPRSS2 (0.36) | ACVRL1PIK3CDTMPRSS2TNK2 | |
| SCHEMBL18666907 | 0.81 | TMPRSS2 (0.36) | ACVRL1PIK3CDTMPRSS2TNK2 | |
| SCHEMBL18666854 | 0.81 | TNK2 (0.35) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |