Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27122220 | 0.90 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL24791279 | 0.87 | L3MBTL1 (0.34) | MIFALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL25723098 | 0.87 | DOT1L (0.33) | DOT1LPOLRMTALDH1A1HPGD | |
| SCHEMBL24606280 | 0.87 | DOT1L (0.35) | DOT1LPOLRMT | |
| SCHEMBL27121538 | 0.85 | TNK2 (0.38) | DOT1LPOLRMT | |
| SCHEMBL27121214 | 0.85 | DOT1L (0.34) | DOT1L | |
| SCHEMBL24606310 | 0.84 | DOT1L (0.36) | DOT1LPOLRMT | |
| SCHEMBL24606256 | 0.84 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL25915184 | 0.84 | DOT1L (0.34) | MIFDOT1LPOLRMTALDH1A1HPGD | |
| SCHEMBL24606327 | 0.84 | DOT1L (0.34) | DOT1LPOLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |