SCHEMBL27122220

SCHEMBL27122220

CN1CCC(CC(=O)OC[C@@H]2CC[C@H](c3ccc4c(N)ncnn34)O2)CC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DOT1L Q8TEK3 3/20 0.34
▸ PRMT5 O14744 2/20 0.32
▸ WDR77 Q9BQA1 2/20 0.32
▸ METTL3 Q86U44 1/20 0.32
▸ DGAT1 O75907 1/20 0.31
▸ POLRMT O00411 1/20 0.31
▸ HTR4 Q13639 1/20 0.30
▸ TLR7 Q9NYK1 2/20 0.30
▸ AXL P30530 1/20 0.30
▸ MERTK Q12866 1/20 0.30
▸ MAP4K4 O95819 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24791261 0.90 MIF (0.34) DOT1LPOLRMT
SCHEMBL24606280 0.86 DOT1L (0.35) DOT1LPOLRMT
SCHEMBL27121214 0.85 DOT1L (0.34) DOT1LDGAT1
SCHEMBL24606310 0.84 DOT1L (0.36) DOT1LPOLRMT
SCHEMBL24606256 0.84 DOT1L (0.34) DOT1LPOLRMT
SCHEMBL26027103 0.82 DOT1L (0.36) DOT1LPOLRMT
SCHEMBL24606262 0.82 DOT1L (0.36) DOT1LPOLRMT
SCHEMBL26237796 0.82 CSNK2A2 (0.35) DOT1LPOLRMTMAP4K4
SCHEMBL24606327 0.81 DOT1L (0.34) DOT1LPOLRMT
SCHEMBL24606316 0.81 DOT1L (0.34) DOT1LPOLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4328227-A1 NUCLEOSIDE COMPOUND AND APPLICATION THEREOF IN THE TREATMENT OF FELINE INFECTIOUS PERITONITIS Vigonvita Life Sciences Co., Ltd. (CN) 2024-02-28 — — EP disclosed
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