⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909771 | 0.89 | TMPRSS2 (0.34) | — | |
| SCHEMBL25913494 | 0.87 | POLRMT (0.31) | — | |
| SCHEMBL24312590 | 0.85 | PI4KA (0.30) | — | |
| SCHEMBL26149082 | 0.84 | — | — | |
| SCHEMBL26200466 | 0.83 | RIPK1 (0.32) | — | |
| SCHEMBL24312557 | 0.82 | NLRP3 (0.31) | — | |
| SCHEMBL25909712 | 0.80 | TMPRSS2 (0.35) | — | |
| SCHEMBL26149007 | 0.80 | RIPK1 (0.30) | — | |
| SCHEMBL18636479 | 0.79 | PI4KA (0.40) | — | |
| SCHEMBL26878947 | 0.79 | PI4KA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |