Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170771 | 0.82 | ELANE (0.41) | ALOX5NQO2HTR2AEGFRKDR | |
| SCHEMBL24791028 | 0.79 | PDE4A (0.49) | AXLPDE4APDE4DALOX5PTGS2 | |
| SCHEMBL15819106 | 0.74 | NTSR1 (0.49) | PDE4APDE4DPGK1ELANE | |
| SCHEMBL24792079 | 0.73 | L3MBTL1 (0.36) | AXLJAK3MKNK1STING1ESR1 | |
| SCHEMBL5040481 | 0.73 | ESR1 (0.40) | AXLPDE4APDE4DALOX5PTGS2 | |
| SCHEMBL15819418 | 0.72 | NTSR1 (0.51) | PDE4APDE4DPGK1ELANE | |
| SCHEMBL24792437 | 0.71 | PDE4D (0.45) | PDE4APDE4DKDR | |
| SCHEMBL20355452 | 0.71 | JAK3 (0.51) | JAK3MKNK1EGFRKDR | |
| SCHEMBL15819572 | 0.71 | HTT (0.41) | PDE4APDE4DPOLBEGFRKDR | |
| SCHEMBL15818956 | 0.71 | NTSR1 (0.52) | PDE4APDE4DPOLBELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262691-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |