Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20983702 | 0.79 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL27637538 | 0.78 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL3702161 | 0.78 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL24793478 | 0.78 | ADRB2 (0.56) | ADRB2TRPV1MAOBCYP2A6HRH3 | |
| SCHEMBL6195448 | 0.78 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4972991 | 0.78 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL27600560 | 0.78 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL30115293 | 0.78 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL24791674 | 0.77 | ADRB2 (0.47) | ADRB2TRPV1MAOBCYP2A6HRH3 | |
| SCHEMBL15624412 | 0.76 | TRPV1 (0.47) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940427-A | Substituted pyrazolo [1,5-a ] pyrimidine-7-amine compounds as CDK inhibitors and therapeutic uses thereof | 卡里克治疗有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-4355426-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE | Carrick Therapeutics Limited (IE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263604-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE | Carrick Therapeutics Limited (IE) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022263604-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE | Carrick Therapeutics Limited (IE) | 2022-12-22 | — | — | WO | disclosed |
| CN-1820007-A | Aryl-substituted benzo[d]isothiazol-3-ylamine analogues as capsaicin receptor modulators | NEUROGEN CORP (US) | 2006-08-16 | — | — | CN | disclosed |