Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170830 | 0.86 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL24792638 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2ALOX5PIK3CAEGFRENPP1 | |
| SCHEMBL24792643 | 0.79 | SMN1; SMN2 (0.35) | SMN1; SMN2ALOX5PIK3CAEGFR | |
| SCHEMBL30170858 | 0.74 | ALOX5 (0.39) | SMN1; SMN2ALOX5EGFR | |
| SCHEMBL24792869 | 0.73 | PDE4A (0.36) | SMN1; SMN2EGFRENPP1 | |
| SCHEMBL30170859 | 0.73 | PDE4A (0.36) | SMN1; SMN2EGFRENPP1PDE10A | |
| SCHEMBL30170868 | 0.70 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL24791345 | 0.69 | MEN1 (0.33) | SMN1; SMN2ALOX5PIK3CAPDE10A | |
| SCHEMBL2725537 | 0.66 | ENPP1 (0.47) | SMN1; SMN2ENPP1PDE10A | |
| SCHEMBL15819368 | 0.65 | ENPP1 (0.51) | SMN1; SMN2ENPP1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262691-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |