Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170830 | 0.89 | ALOX5 (0.39) | ALOX5ELANEPDGFRBPDGFRAEPHA2 | |
| SCHEMBL30170868 | 0.84 | ALOX5 (0.38) | ALOX5ELANEPDGFRBPDGFRAEPHA2 | |
| SCHEMBL30170771 | 0.77 | ELANE (0.41) | ALOX5ELANEPDGFRBPDGFRAEPHA2 | |
| SCHEMBL30170824 | 0.75 | SOS1 (0.35) | ALOX5ELANEPDGFRBPDGFRAEPHA2 | |
| SCHEMBL24792178 | 0.74 | SMN1; SMN2 (0.36) | ALOX5EGFRSMN1; SMN2 | |
| SCHEMBL24791345 | 0.73 | MEN1 (0.33) | ALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL24792638 | 0.69 | SMN1; SMN2 (0.39) | ALOX5EGFRSMN1; SMN2 | |
| SCHEMBL15819502 | 0.68 | NTSR1 (0.59) | ALOX5ELANENTSR1KDM4EALDH1A1 | |
| SCHEMBL19385357 | 0.65 | ELANE (0.55) | ELANEPDGFRBPDGFRAEGFRKDM4E | |
| SCHEMBL24792643 | 0.65 | SMN1; SMN2 (0.35) | ALOX5EGFRALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262691-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |