Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24792643 | 0.88 | SMN1; SMN2 (0.35) | MEN1KMT2APIK3CAALOX5SMN1; SMN2 | |
| SCHEMBL30170858 | 0.73 | ALOX5 (0.39) | ALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL24792079 | 0.73 | L3MBTL1 (0.36) | MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL24792638 | 0.72 | SMN1; SMN2 (0.39) | PIK3CAALOX5SMN1; SMN2PDE10A | |
| SCHEMBL24792644 | 0.71 | SOS1 (0.52) | — | |
| SCHEMBL24792178 | 0.69 | SMN1; SMN2 (0.36) | PIK3CAALOX5SMN1; SMN2PDE10A | |
| SCHEMBL24792471 | 0.67 | TYK2 (0.35) | ALOX5 | |
| SCHEMBL30170833 | 0.67 | TYK2 (0.35) | ALOX5 | |
| SCHEMBL30170830 | 0.64 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL24792869 | 0.61 | PDE4A (0.36) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262691-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |