SCHEMBL2479296

SCHEMBL2479296

CCCC[Sn](CCCC)(CCCC)c1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.56
ITGA2B P08514 2/20 0.56
ACE P12821 1/20 0.54
ITGA4 P13612 1/20 0.49
ITGB7 P26010 1/20 0.49
CTSK P43235 7/20 0.48
CTSS P25774 6/20 0.48
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
PPARA Q07869 5/20 0.47
PPARG P37231 4/20 0.47
PTPN1 P18031 2/20 0.46
ITGB1 P05556 1/20 0.46
ITGAV P06756 1/20 0.46
ITGB5 P18084 1/20 0.46
PPARD Q03181 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22023204 1.00 ITGB3 (0.56) ITGB3ITGA2BACEITGA4ITGB7
SCHEMBL2720546 0.90 KLK5 (0.49) ITGB3ITGA2BACEITGA4ITGB7
SCHEMBL2480406 0.90 KLK5 (0.49) ITGB3ITGA2BACEITGA4ITGB7
SCHEMBL8098713 0.87 CTSK (0.49) ACECTSKCTSSCTSLCTSB
SCHEMBL2477418 0.85 CTSS (0.53) CTSKCTSSCTSLCTSBPTPN1
SCHEMBL1819429 0.84 CTSK (0.41) ITGB3ITGA2BACECTSKCTSS
SCHEMBL5731512 0.83 ACE (0.60) ITGB3ITGA2BACEITGA4ITGB7
SCHEMBL5731509 0.83 ACE (0.60) ITGB3ITGA2BACEITGA4ITGB7
SCHEMBL5731514 0.83 ACE (0.60) ITGB3ITGA2BACEITGA4ITGB7
SCHEMBL6685168 0.82 ITGB3 (0.79) ITGB3ITGA2BACEITGA4PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388522-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND OSAKA UNIVERSITY (JP) 2025-12-25 US disclosed
US-12421179-B2 Production method for radiolabeled aryl compound OSAKA UNIVERSITY (JP) 2025-09-23 US disclosed
EP-3663307-B1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND UNIV OSAKA (JP) 2024-10-02 EP disclosed
EP-4438608-A2 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND Osaka University (JP) 2024-10-02 EP disclosed
US-20230331640-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND OSAKA UNIVERSITY (JP) 2023-10-19 US disclosed
US-11731917-B2 Production method for radiolabeled aryl compound OSAKA UNIVERSITY (JP) 2023-08-22 US disclosed
US-20200369578-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND OSAKA UNIVERSITY (JP) 2020-11-26 US disclosed
EP-3663307-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND Osaka University (JP) 2020-06-10 EP disclosed
US-9024093-B2 Fluorination of organic compounds PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-05-05 US disclosed
WO-2012054782-A2 FLUOROALKOXYLATION OF ORGANIC COMPOUNDS PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) 2012-04-26 WO disclosed
US-20110312903-A1 FLUORINATION OF ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2011-12-22 US disclosed
EP-2376408-A2 FLUORINATION OF ORGANIC COMPOUNDS President and Fellows of Harvard College (US) 2011-10-19 EP disclosed
WO-2010059943-A2 FLUORINATION OF ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331640-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND NAT1, CAT, ARSA ITGB3 2991/4885ITGA2B 2479/4885ACE 806/4885
US-20250388522-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND CYP2C9, CYP2C19, CYP2B6 ITGB3 2521/4885ITGA2B 2940/4885ACE 2758/4885
US-11731917-B2 Production method for radiolabeled aryl compound NAT1, CAT, ARSA ITGB3 2991/4885ITGA2B 2479/4885ACE 806/4885
US-20200369578-A1 PRODUCTION METHOD FOR RADIOLABELED ARYL COMPOUND NAT1, CAT, ARSA ITGB3 2991/4885ITGA2B 2479/4885ACE 806/4885
US-20110312903-A1 FLUORINATION OF ORGANIC COMPOUNDS SLCO1B3, SLCO2B1, FLI1 ITGB3 323/4885ITGA2B 961/4885ACE 3215/4885
US-12421179-B2 Production method for radiolabeled aryl compound NAT1, CAT, ARSA ITGB3 2991/4885ITGA2B 2479/4885ACE 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.