SCHEMBL24794868

SCHEMBL24794868

CC1CN(c2ccc(S)cc2)C(=O)O1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 16/20 0.40
FADS1 O60427 1/20 0.38
F10 P00742 1/20 0.37
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550258 0.84 GRM2 (0.55) GRM2FADS1F10
SCHEMBL14168504 0.84 GRM2 (0.55) GRM2FADS1F10
SCHEMBL14540825 0.84 GRM2 (0.55) GRM2
SCHEMBL9550256 0.83 GRM2 (0.40) GRM2FADS1F10HTR6
SCHEMBL30162780 0.83 ALDH1A1 (0.46) GRM2
SCHEMBL31192184 0.83 ALDH1A1 (0.46) GRM2
SCHEMBL24852630 0.83 ALDH1A1 (0.46) GRM2
SCHEMBL24794874 0.83 GRM2 (0.56) GRM2FADS1F10HTR6
SCHEMBL6266797 0.82 GRM2 (0.57) GRM2FADS1
SCHEMBL20874535 0.80 GRM2 (0.53) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11529621-B1 Nickel-based metal-organic framework as catalyst for chemical fixation of CO2 in oxazolidinone synthesis KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529621-B1 Nickel-based metal-organic framework as catalyst for chemical fixation of CO2 in oxazolidinone synthesis BTF3, FZD7, POF1B GRM2 2372/4885FADS1 2929/4885F10 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.